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Programm & Abstracts "Innovationen in der Augenheilkunde" | |
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Effects of TGF-ß1 and TGF-ß2 on Proliferation, Migration and Matrix Production of Cultured Human Tenon's Capsule Fibroblasts in Pseudoexfoliation and Primary Open Angle Glaucoma 1Kottler U. B., 2Schlötzer-Schrehardt U., 2Zenkel M., 2Küchle M., 2Jünemann A., 2Naumann G. O. H.,
Purpose: Significantly increased aqueous levels of TGF-ß1 in pseudoexfoliation (PEX) syndrome/glaucoma and TGF-ß2 in primary open-angle glaucoma (POAG) may adversely affect the outcome of glaucoma filtration surgery. We investigated the effects of TGF-ß1 and -ß2 on proliferation, migration and extracellular matrix production of cultured Tenon's capsule fibroblasts derived from PEX, POAG, and cataract control patients. |
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