
Aktuelle Tagungsinformationen
News and Updates
Anmeldung zur Tagung
Registration
Hotelbuchung
Hotel Registration
Grußwort
Welcome address
Beteiligte Gesellschaften
Societies involved
Eröffnung des Kongresses
Opening Ceremony
Preise
Awards
Wissenschaftliches Programm
Scientific program
Posterpräsentationen
Poster Presentation
Kurse
Courses
Begleitende Veranstaltungen
Collateral Events
Rahmenprogramm
Social program
Jubiläumsparty
Jubilee Party
DOG Information
DOG Information
Allgemeine Informationen
General Information
Autorenindex
Index of Authors
Ausstellerliste
Exhibitors
Sponsoren
Sponsors
Teilnahmegebühren
Registration fees
Impressum
DOG Homepage
|
2-year-results of Photodynamic Therapy (PDT) for 55 Patients with Age-related Macular Degeneration
Mörchen M., Ungerechts R., Emmerich K.-H., Städtische Kliniken Darmstadt, Augenklinik (Darmstadt)
Purpose: In the eye-clinic Darmstadt, a PDT was carried out on 91 patients from 02/00 to 02/02 on the basis of an age-related macular-degeneration. The patients, with whom a PDT was started in the time period from 02/00 to 03/01 were evaluated (n = 55 patients). The individual therapy-course will be demonstrated by selected cases. Method: The following parameters were derived from the first and following examinations: Ophthalmologic and general anamnesis, visual acuity, examination of metamorphopsia and central skotoma by means of Amsler`s chart, measurement of an existing macular edema by ultrasonography in the sagittal section (B-mode) and classification of the AMD by fluorescein-angiographic means into following subgroups: Predominantly classic, mixed and occult CNV. The technical implementation of the PDT took place according to the protocols of the TAP-studies. Control examinations took place after three months. Results: Out of 55 patients, 16 patients showed a classic CNV, 27 patients mixed CNC and 12 patients occult CNV. Results of the patients with classic CNV: 50% stabilization or amelioration of visual acuity; reduction of macular edema from 0,65mm to 0,25mm; reduced fluoresceinleakage with 50-62,5% after each treatment; stabilization or amelioration of the metamorphopsias with 92,8-93,8% after each treatment. Mixed CNV: 53% stabilization or amelioration of visual acuity; reduction of macular edema from 0,72 to 0,41mm; reduced fluoresceinleakage with 76-91%; stabilization or amelioration of the metamorphopsias 83-90%. Occult CNV: 64% stabilization or amelioration of visual acuity; reduction of macular edema from 0,71 to 0,35mm; reduced fluoresceinleakage with 87-91%; stabilization or amelioration of metamorphopsias 83,3-100%. Conclusions: Patients with classic, mixed and occult CNV can profit from the PDT if an active CNV is present. The results of the TAP- and VIP-studies are confirmed in the clinical application. The B-mode-echographie proves to be a simple and feasible aid to the clinical course of observation.
Zurück/Back
|