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Frequency of Reoperations after Amniotic Membrane Transplantation
1Denk P. O., 2Deuter C. M. E., 1von Eicken J., 3Knorr M.,
1Eberhard-Karls-Universität Tübingen, Universitäts-Augenklinik, Abt. I (Tübingen)
2Eberhard-Karls-Universität Tübingen, Universitäts-Augenklinik, Erkrankungen des vorderen und hinteren Augenabschnittes (Tübingen)
3Städtisches Klinikum Krefeld, Augenklinik (Krefeld)
Purpose: Retrospective evaluation of the frequency of reoperations after amniotic membrane transplantation for different pathologic entities.
Method: We included all amniotic membrane transplantations (AMT), which were performed at the university eye clinic Tübingen since 1997 and which had been followed up for at least 12 months. Patients diagnosis were subdivided as follows: Conjunctival defects after tumor excision (n=3), Bullous keratopathy (n=4), External Fistula after glaucoma filtering surgery (n=3), Recurrent Pterygium (n=4), Symblepharon (n=6), Corneal ulcer with descemetocele (n=3), non-perforated corneal ulcer (n=52), perforated corneal ulcer (n=3), Other (n=2).
Results: The overall reoperation rate was determined to be 42% after a follow-up period of one year. Most frequently, a second AMT (n=14) and a perforating keratoplasty (n=13) were performed after the initial AMT. The following reoperation rates were determined for the subgroups: Conjunctival defects after tumor excision (0%), Bullous keratopathy (75%), External Fistula after glaucoma filtering surgery (66%), Recurrent Pterygium (50%), Symblepharon (66%), Corneal ulcer with descemetocele (66%), non-perforated corneal ulcer (38%), perforated corneal ulcer (66%).
Conclusions: Particularly in patients with conjunctival defects after tumor excision and with non-perforated corneal ulcers, stabilization of the ocular surface homeostasis can be achieved with the a single amniotic membrane transplantation for at least one year.